Description

Laxaphycin B is a potent cyclic lipopeptide natural product, a member of the laxaphycin family known for its complex structure and significant biological activity. This compound is of high interest for its role in chemical biology research and as a lead structure in the discovery of novel bioactive agents. It is primarily utilized by research institutions and pharmaceutical development teams focused on oncology, antimicrobial discovery, and molecular probe development.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating its mechanism of action, particularly its reported cytotoxic and antifungal properties.
• Drug Discovery & Development: Serves as a critical lead compound for the synthesis of analogs and derivatives aimed at improving pharmacological profiles for potential therapeutic applications.
• Chemical Biology: Employed as a molecular tool to study specific biological pathways and protein interactions due to its selective bioactivity.
• Antimicrobial Research: Investigated for its efficacy against various fungal and bacterial strains in academic and industrial microbiology labs.
• Oncology Research: Studied in vitro and in vivo for its potential anti-proliferative effects against various cancer cell lines.
• Natural Product Chemistry: Used as a high-purity analytical standard for the identification and quantification of laxaphycins in complex matrices.

Basic Information

Product Name	Laxaphycin B
CAS No.	144941-08-2
Molecular Formula	C54H86N12O13
Molecular Weight	1087.3 g/mol
Synonyms	Laxaphycin B; [Ile7]-Laxaphycin B; Cyclo[L-Val-D-Leu-L-Ile-D-Leu-L-Leu-D-Leu-L-Ile-D-Leu-L-Leu-D-Leu-L-Leu-D-Leu]; Laxaphycin B (cyclic lipopeptide); Cyanobacterial lipopeptide B; Lax B
EINECS	Contact for details

Quality Control

Our Laxaphycin B is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant standards for high-purity research chemicals, ensuring reliable performance in sensitive biological assays.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.