Description

5-[[4-(4-Propoxyphenyl)Piperazin-1-Yl]Methyl]-4,5-Dihydro-1,3-Oxazol-2 -Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperazine-oxazoline hybrid structure. This compound is critical for research and development in medicinal chemistry, offering a versatile scaffold for the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and cardiovascular drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates targeting various receptors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Preclinical Drug Development: Essential for producing compounds for pharmacological screening and early-stage toxicology studies.
• Reference Standard: Employed as an analytical standard for quality control and method development in API manufacturing.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke molecules for client projects.

Basic Information

Product Name	5-[[4-(4-Propoxyphenyl)Piperazin-1-Yl]Methyl]-4,5-Dihydro-1,3-Oxazol-2 -Amine
CAS No.	144881-41-4
Molecular Formula	C17H26N4O2
Molecular Weight	318.42 g/mol
Synonyms	2-Amino-5-[[4-(4-propoxyphenyl)-1-piperazinyl]methyl]-4,5-dihydrooxazole; 5-((4-(4-Propoxyphenyl)piperazin-1-yl)methyl)-4,5-dihydrooxazol-2-amine; 2-Amino-5-[(4-(4-propoxyphenyl)piperazin-1-yl)methyl]-2-oxazoline; 144881-41-4; UNII-9F4H8O3V8R; 9F4H8O3V8R; Oxazol-2-amine, 4,5-dihydro-5-[[4-(4-propoxyphenyl)-1-piperazinyl]methyl]-
EINECS	Contact for details

Quality Control

Our 5-[[4-(4-Propoxyphenyl)Piperazin-1-Yl]Methyl]-4,5-Dihydro-1,3-Oxazol-2 -Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.