Description

1,2-Bis(10,12-Tricosadiynoyl)-Sn-Glycero-3-Phosphoethanolamine is a specialized synthetic phospholipid, specifically a diacetylenic phosphatidylethanolamine derivative, with the CAS number 144750-73-2. This compound is a critical building block in advanced materials science and biophysical research, valued for its unique ability to undergo topochemical polymerization upon exposure to UV light. It is essential for researchers and product developers in the fields of biosensor fabrication, drug delivery system modeling, and the creation of polymerizable biomimetic membranes. Its precise structure enables the study of membrane dynamics and the development of stable, patterned surfaces for diagnostic and nanotechnology applications.

Application

• Polymerizable Lipid Bilayer Research: A key component for creating stable, cross-linked model membranes to study biophysical properties and membrane protein interactions.
• Biosensor Development: Used to fabricate robust, patterned sensor surfaces that can immobilize biological recognition elements.
• Advanced Drug Delivery Systems: Serves as a model compound for designing and testing stimuli-responsive liposomal and nanoparticle carriers.
• Nanotechnology and Material Science: Enables the production of novel polymeric nanostructures and thin films with tailored surface properties.
• Photolithography and Micro-patterning: Utilized in photopolymerization processes to create precise microscopic patterns on surfaces for lab-on-a-chip and diagnostic devices.
• Membrane Biophysics Studies: Fundamental tool for investigating lipid-lipid and lipid-protein interactions in a controlled, polymerizable environment.

Basic Information

Item	Details
Product Name	1,2-Bis(10,12-Tricosadiynoyl)-Sn-Glycero-3-Phosphoethanolamine
CAS No.	144750-73-2
Molecular Formula	C52H88NO8P
Molecular Weight	878.23 g/mol
Synonyms	1,2-Bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphoethanolamine; Diyne PE Lipid; DC8,9PE; Polymerizable Phosphatidylethanolamine; 1,2-di(10,12-tricosadiynoyl)-sn-glycero-3-phosphoethanolamine; Phospholipid DC8,9; Diacetylenic Phospholipid; Tricosadiynoyl Phosphoethanolamine
EINECS	Contact for details

Quality Control

Every batch of 1,2-Bis(10,12-Tricosadiynoyl)-Sn-Glycero-3-Phosphoethanolamine is produced and analyzed under strict quality protocols to ensure high purity and consistency for research applications. Our quality assurance includes comprehensive analytical testing via HPLC, NMR, and MS to confirm identity, purity, and the integrity of the diacetylene functionality. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. This compound is hygroscopic (moisture-sensitive) and easily oxidized. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in chloroform, DCM; slightly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.