Description

(3S,5S,6R)-3-(3-Butenyl)-2-Oxo-5,6-Diphenyl-4-Morpholinecarboxylic Acid tert-Butyl Ester is a sophisticated chiral morpholine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its well-defined stereochemistry and functional groups, which enable the precise construction of complex molecular architectures. This high-purity intermediate is essential for research and development teams in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients with specific biological activities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring stereochemical precision.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides where specific stereoisomers exhibit enhanced efficacy.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of novel chiral catalysts for stereoselective reactions.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis organizations (CSOs) producing bespoke compounds for client R&D pipelines.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and the study of heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	(3S,5S,6R)-3-(3-Butenyl)-2-Oxo-5,6-Diphenyl-4-Morpholinecarboxylic Acid tert-Butyl Ester
CAS No.	144542-72-3
Molecular Formula	C25H29NO4
Molecular Weight	407.51 g/mol
Synonyms	tert-Butyl (3S,5S,6R)-3-(but-3-en-1-yl)-2-oxo-5,6-diphenylmorpholine-4-carboxylate; 4-Morpholinecarboxylic acid, 3-(3-butenyl)-2-oxo-5,6-diphenyl-, 1,1-dimethylethyl ester, (3S,5S,6R)-; (3S,5S,6R)-3-But-3-en-1-yl-2-oxo-5,6-diphenyl-1,4-oxazinane-4-carboxylic acid tert-butyl ester; Chiral Morpholine Ester; BOC-Protected Morpholine Derivative
EINECS	Contact for details

Quality Control

Our production of (3S,5S,6R)-3-(3-Butenyl)-2-Oxo-5,6-Diphenyl-4-Morpholinecarboxylic Acid tert-Butyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and stereochemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be handled in accordance with good laboratory practices for fine chemicals.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.