Description

3-(4-Acetyl-Piperazin-1-Yl)-4-Chloroaniline is a high-purity, advanced pharmaceutical intermediate characterized by its distinct molecular architecture. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where its specific functional groups enable targeted chemical modifications. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides due to its aniline and piperazine-derived structure.
• Chemical Synthesis: Serves as a versatile building block for creating complex heterocyclic compounds and fine chemicals in laboratory and pilot-scale production.
• Material Science: Potential monomer or modifier in the research of specialty polymers and advanced functional materials.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	3-(4-Acetyl-Piperazin-1-Yl)-4-Chloroaniline
CAS No.	144514-38-5
Molecular Formula	C12H16ClN3O
Molecular Weight	253.73 g/mol
Synonyms	4-Chloro-3-(4-acetylpiperazin-1-yl)aniline; 1-[5-Amino-2-chlorophenyl]-4-acetylpiperazine; 3-(4-Acetyl-1-piperazinyl)-4-chloroaniline; 4-Chloro-3-(1-piperazinyl)aniline, 1-acetyl-; 144514-38-5; 4-Chloro-3-(4-acetylpiperazin-1-yl)benzenamine; N-[4-Chloro-3-(4-acetyl-1-piperazinyl)phenyl]amine
EINECS	Contact for details

Quality Control

Our 3-(4-Acetyl-Piperazin-1-Yl)-4-Chloroaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.