Description

9H,11H-Pyrazino(2,1-C)Pyrrolo(1,2-A)(1,4)Benzodiazepin-11-One, 12,13,14,14A-Tetrahydro-13-Acetyl- is a complex heterocyclic compound that serves as a critical advanced intermediate in modern pharmaceutical synthesis. This compound is valued for its intricate fused-ring structure, which provides a versatile scaffold for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in the synthesis of specialized benzodiazepine analogs and other bioactive molecules. The precise chemical architecture of this intermediate enables targeted modifications for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthetic pathway for novel benzodiazepine-derived therapeutics.
• Drug Discovery Research: Used as a core scaffold in medicinal chemistry for designing and testing new chemical entities with potential biological activity.
• Process Chemistry Development: Serves as a critical intermediate for optimizing scalable and efficient API manufacturing processes.
• Academic & Institutional Research: Utilized in chemical and pharmacological studies investigating structure-activity relationships (SAR) of complex heterocycles.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API production.
• Custom Synthesis Starting Material: Provides a foundation for the contract synthesis of specialized, non-commercial compounds for client-specific research programs.

Basic Information

Product Name	9H,11H-Pyrazino(2,1-C)Pyrrolo(1,2-A)(1,4)Benzodiazepin-11-One, 12,13,14,14A-Tetrahydro-13-Acetyl-
CAS No.	144109-17-1
Molecular Formula	C18H17N3O2
Molecular Weight	307.35 g/mol
Synonyms	13-Acetyl-12,13,14,14a-tetrahydro-9H,11H-pyrazino[2,1-c]pyrrolo[1,2-a][1,4]benzodiazepin-11-one; Tetrahydro-13-acetyl-9H,11H-pyrazino(2,1-c)pyrrolo(1,2-a)(1,4)benzodiazepin-11-one; 144109-17-1; 13-Acetyl-12,13,14,14a-tetrahydro-9H-pyrazino[2,1-c]pyrrolo[1,2-a][1,4]benzodiazepin-11-one
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with cGMP guidelines where applicable for non-clinical and development-stage materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere packaging to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.