Description

n-(3,5-Dinitrobenzoyl)-Dl-Proline is a specialized chiral derivatizing agent used for the resolution and analysis of enantiomers. This compound matters for its critical role in ensuring the purity and correct stereochemistry of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions, analytical laboratories, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for chiral separation processes, including HPLC method development and quality control.

Application

• Chiral Resolution Agent: Used as a derivatizing reagent for the separation and analysis of racemic mixtures via High-Performance Liquid Chromatography (HPLC).
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of enantiomerically pure pharmaceutical compounds.
• Analytical Chemistry Standard: Employed as a reference standard in method development and validation for chiral assays.
• Asymmetric Synthesis: Utilized in research and development for creating chiral auxiliaries and catalysts.
• Quality Control (QC) Testing: Essential for the enantiomeric purity testing of APIs and fine chemicals in GMP environments.
• Academic & Industrial Research: A valuable tool for studying stereochemistry and developing new chiral separation methodologies.

Basic Information

Item	Details
Product Name	n-(3,5-Dinitrobenzoyl)-Dl-Proline
CAS No.	143492-62-0
Molecular Formula	C12H11N3O7
Molecular Weight	309.24 g/mol
Synonyms	DNB-Proline; (RS)-N-(3,5-Dinitrobenzoyl)proline; DL-N-(3,5-Dinitrobenzoyl)proline; 3,5-Dinitrobenzoyl-DL-proline; Proline, N-(3,5-dinitrobenzoyl)-, DL-; (DL)-N-(3,5-Dinitrobenzoyl)proline; 1-[(3,5-Dinitrobenzoyl)]-DL-proline
EINECS	Contact for details

Quality Control

Our n-(3,5-Dinitrobenzoyl)-Dl-Proline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for assay and chiral purity, to ensure it meets the high standards required for research and industrial applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-mixture as specified
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.