Description

2-Piperazinecarboxaldehyde, 3,6-Dioxo- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Peptidomimetic Research: Used in the design and synthesis of peptidomimetics and constrained peptide analogs for drug discovery programs.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Agrochemical Development: Acts as a building block for novel herbicides, fungicides, and plant growth regulators.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) settings for methodological development and novel heterocycle synthesis.
• Custom Synthesis Projects: A valuable starting material for custom synthesis and scale-up projects requiring specific piperazine-derived aldehydes.

Basic Information

Product Name	2-Piperazinecarboxaldehyde, 3,6-Dioxo- (9Ci)
CAS No.	143411-84-1
Molecular Formula	C5H8N2O3
Molecular Weight	144.13 g/mol
Synonyms	3,6-Dioxopiperazine-2-carboxaldehyde; 2-Formyl-3,6-dioxopiperazine; 3,6-Dioxo-2-piperazinecarboxaldehyde; 2-Piperazinecarboxaldehyde, 3,6-dioxo-; 2-Aldehydo-3,6-diketopiperazine; 3,6-Dioxopiperazine-2-carbaldehyde; Dioxopiperazine carboxaldehyde; (3,6-Dioxopiperazin-2-yl)methanal
EINECS	Contact for details

Quality Control

Our 2-Piperazinecarboxaldehyde, 3,6-Dioxo- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.