Description

1-Piperazinecarboxaldehyde, 2,5-Dioxo- (9Ci) is a specialized heterocyclic building block featuring both aldehyde and imide functionalities. This compound matters as a versatile synthon for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, where its reactive handles enable the synthesis of fused piperazine derivatives and other nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require complex heterocyclic cores.
• Ligand Synthesis: Serves as a starting material for creating chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Employed in the production of specialty polymers and resins where the incorporation of piperazine units modifies material properties.
• Chemical Biology Probes: Useful for designing activity-based probes and molecular tags for studying biological processes.
• Academic & Institutional Research: A valuable reagent for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-Piperazinecarboxaldehyde, 2,5-Dioxo- (9Ci)
CAS No.	143411-81-8
Molecular Formula	C5H6N2O3
Molecular Weight	142.11 g/mol
Synonyms	2,5-Dioxopiperazine-1-carbaldehyde; 1-Formyl-2,5-piperazinedione; 2,5-Diketopiperazine-1-carboxaldehyde; NSC 405124; Piperazine-2,5-dione-1-carboxaldehyde; 1-Carbamoyl-2,5-diketopiperazine; 1-Aldehydo-2,5-diketopiperazine
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxaldehyde, 2,5-Dioxo- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.