Description

Sodium (2S,5R,6R)-6-[[1-(3-Chlorophenyl)Cyclopentanecarbonyl]Amino]-3, 3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate is a high-purity sodium salt of a complex β-lactam derivative, serving as a critical pharmaceutical intermediate in the synthesis of advanced active pharmaceutical ingredients (APIs). Its precise stereochemistry and functional groups make it an essential building block for research and production in modern medicinal chemistry. This compound is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) focused on developing novel antibacterial agents and other therapeutic molecules.

Application

• Key Intermediate in API Synthesis: Serves as a crucial precursor in the multi-step synthesis of novel β-lactam antibiotics and other complex pharmaceutical compounds.
• Pharmaceutical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new drug candidates targeting bacterial infections.
• Process Chemistry & Scale-Up: Employed in process optimization and pilot-scale production runs for new chemical entities (NCEs) before commercial manufacturing.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control, method development, and regulatory submissions.
• Custom Synthesis Building Block: Provides a specialized starting material for custom synthesis projects requiring a specific, complex β-lactam core structure.

Basic Information

Product Name	Sodium (2S,5R,6R)-6-[[1-(3-Chlorophenyl)Cyclopentanecarbonyl]Amino]-3, 3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate
CAS No.	143407-68-5
Molecular Formula	C22H24ClN2NaO4S
Molecular Weight	470.94 g/mol
Synonyms	Sodium 6β-[[1-(3-Chlorophenyl)cyclopentanecarboxamido]]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2α-carboxylate; Sodium 6β-(1-(3-Chlorophenyl)cyclopentanecarboxamido)penicillanate; (2S,5R,6R)-6-[(1-(3-Chlorophenyl)cyclopentanecarboxamido)]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt; Sodium penicillanate derivative; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid derivative sodium salt
EINECS	Contact for details

Quality Control

Our Sodium (2S,5R,6R)-6-[[1-(3-Chlorophenyl)Cyclopentanecarbonyl]Amino]-3, 3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistent quality, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and prevent degradation. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.