Description

2,5-Piperazinedione, 3-(Hydroxymethylene)-6-Phenyl- is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key precursor for the development of novel pharmaceutical intermediates and bioactive molecules, particularly in medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon in the synthesis of potential drug candidates, especially those targeting neurological or oncological pathways.
• Peptidomimetic Research: Used in the design and construction of peptidomimetics and constrained peptide analogs due to its piperazinedione core.
• Agrochemical Development: Acts as a building block for novel active ingredients in crop protection research.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal complexation studies.
• Academic & Institutional R&D: Utilized in universities and research institutes for methodological studies in heterocyclic and medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.

Basic Information

Product Name	2,5-Piperazinedione, 3-(Hydroxymethylene)-6-Phenyl-
CAS No.	142975-48-2
Molecular Formula	C11H10N2O3
Molecular Weight	218.21 g/mol
Synonyms	3-(Hydroxymethylene)-6-phenylpiperazine-2,5-dione; 6-Phenyl-3-(hydroxymethylene)piperazine-2,5-dione; 3-Formyl-6-phenyl-2,5-piperazinedione; 3-(Hydroxymethylene)-6-phenyl-2,5-diketopiperazine; 6-Phenyl-3-(hydroxymethylene)-2,5-diketopiperazine; 3-Hydroxymethylene-6-phenyl-2,5-diketopiperazine; 142975-48-2 (CAS Index Name)
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedione, 3-(Hydroxymethylene)-6-Phenyl- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality systems support development from research quantities to pilot-scale cGMP production, ensuring reliable supply for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.