Description

(-)-n-(3-Methoxypropyl)-1-Phenyl-2-Pyrrolidinemethanamine Fumarate is a high-purity, chiral organic salt primarily utilized as a critical pharmaceutical intermediate. Its value lies in its defined stereochemistry and salt form, which are essential for ensuring the efficacy and consistency of final active pharmaceutical ingredients (APIs). This compound is specifically required by research institutions and manufacturers in the pharmaceutical and fine chemical sectors engaged in the development and production of specialized therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel chiral drug candidates, particularly in central nervous system (CNS) research.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control testing in GMP environments.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective chemical reactions to create enantiomerically pure compounds.
• Preclinical & Clinical Research: Serves as a starting material for producing compounds used in pharmacological studies and early-stage drug development.
• Process Chemistry: Used in route scouting and optimization for the scalable manufacturing of complex organic molecules.

Basic Information

Product Name	(-)-n-(3-Methoxypropyl)-1-Phenyl-2-Pyrrolidinemethanamine Fumarate
CAS No.	142469-86-1
Molecular Formula	C19H28N2O • C4H4O4
Molecular Weight	416.48 g/mol
Synonyms	(-)-N-(3-Methoxypropyl)-1-phenyl-2-pyrrolidinemethanamine fumarate; (2R)-1-Phenyl-2-[(3-methoxypropyl)amino]methylpyrrolidine fumarate; (R)-N-(3-Methoxypropyl)-1-phenyl-2-(pyrrolidin-2-yl)methanamine fumarate; Levopropylhexedrine fumarate (related); Fumarate salt of a chiral pyrrolidine derivative; (R)-1-Phenyl-2-((3-methoxypropyl)amino)methylpyrrolidine fumarate
EINECS	Contact for details

Quality Control

Our (-)-n-(3-Methoxypropyl)-1-Phenyl-2-Pyrrolidinemethanamine Fumarate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be customized to meet specific project or regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.