Description

2-(Piperazin-2-Yl)Acetonitrile Dihydrochloride is a high-purity, versatile chemical intermediate with significant utility in advanced organic synthesis. Its core value proposition lies in its role as a critical building block for constructing complex nitrogen-containing heterocycles, which are fundamental to modern pharmaceutical discovery and development. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific piperazine-based scaffolds.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Peptidomimetic Chemistry: Integral for constructing non-peptide scaffolds that mimic the structure and function of peptides in medicinal chemistry.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	2-(Piperazin-2-Yl)Acetonitrile Dihydrochloride
CAS No.	142054-62-4
Molecular Formula	C6H12N4·2HCl
Molecular Weight	209.10 g/mol
Synonyms	2-(Piperazin-2-yl)acetonitrile dihydrochloride; 2-(2-Piperazinyl)acetonitrile dihydrochloride; 2-Piperazin-2-ylacetonitrile dihydrochloride; Acetonitrile, 2-(2-piperazinyl)-, dihydrochloride; 2-(Piperazin-2-yl)ethanenitrile dihydrochloride; (Piperazin-2-yl)acetonitrile dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Piperazin-2-Yl)Acetonitrile Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full traceability are provided for every shipment, and we support compliance with relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.