Description

14-Deoxy-11,12-Didehydroandrographiside is a bioactive diterpenoid lactone derived from the medicinal plant *Andrographis paniculata*. This compound is of significant interest for its role as a key intermediate and reference standard in the research and development of novel therapeutic agents. It is primarily utilized by the pharmaceutical, nutraceutical, and academic research sectors for analytical and pharmacological studies.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of Andrographis extracts and finished products in quality control laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical precursor in the synthesis of more complex andrographolide derivatives for drug development.
• Biochemical Research: Employed in *in vitro* and *in vivo* studies to investigate anti-inflammatory, antiviral, and immunomodulatory mechanisms of action.
• Nutraceutical Standardization: Acts as a marker compound to standardize herbal supplements and ensure batch-to-batch consistency of *Andrographis paniculata* formulations.
• Analytical Method Development: Essential for developing and validating HPLC, LC-MS, and other chromatographic methods in analytical chemistry.

Basic Information

Product Name	14-Deoxy-11,12-Didehydroandrographiside
CAS No.	141973-41-3
Molecular Formula	C₂₀H₃₀O₅
Molecular Weight	350.45 g/mol
Synonyms	14-Deoxy-11,12-didehydroandrographolide; DDAG; 14-Deoxy-δ¹¹,¹²-Andrographolide; 3-[2-[Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone; Andrographolide derivative; 14-Deoxy-δ¹¹-Andrographolide
EINECS	Contact for details

Quality Control

Our 14-Deoxy-11,12-Didehydroandrographiside is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.