Description

Ethyl 3-Hydroxy-5-Methylpyrazine-2-Carboxylate is a high-purity pyrazine derivative, a crucial heterocyclic building block valued for its structural complexity and functional versatility. This compound is essential for the synthesis of advanced pharmaceutical intermediates and fine chemicals, offering a reliable foundation for research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the pyrazine core for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Flavor and Fragrance Industry: Acts as a potential intermediate for synthesizing complex aroma compounds due to the pyrazine ring's characteristic nutty, roasted notes.
• Material Science Research: Investigated as a building block for organic electronic materials and metal-organic frameworks (MOFs).
• Academic and R&D Laboratories: A valuable reference standard and starting material for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	Ethyl 3-Hydroxy-5-Methylpyrazine-2-Carboxylate
CAS No.	141872-22-2
Molecular Formula	C8H10N2O3
Molecular Weight	182.18 g/mol
Synonyms	5-Methyl-3-hydroxypyrazine-2-carboxylic acid ethyl ester; Ethyl 5-methyl-3-oxo-3,4-dihydro-2-pyrazinecarboxylate; 3-Hydroxy-5-methylpyrazine-2-carboxylic acid ethyl ester; 2-Pyrazinecarboxylic acid, 3-hydroxy-5-methyl-, ethyl ester; Ethyl 3-hydroxy-5-methyl-2-pyrazinecarboxylate; 5-Methyl-3-hydroxypyrazine-2-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-Hydroxy-5-Methylpyrazine-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.