Description

4-Amino-1-Methylpiperidine-4-Carboxylic Acid Hydrochloride is a high-purity, functionalized piperidine derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique structure, featuring both amino and carboxylic acid functional groups on the same carbon, makes it invaluable for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where its piperidine scaffold can contribute to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics and Bioactive Molecule Synthesis: Its structure is ideal for incorporating constrained amino acid analogs into peptides and other bioactive compounds to modulate stability and receptor interaction.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects at various scales, from research to pilot plant.

Basic Information

Item	Detail
Product Name	4-Amino-1-Methylpiperidine-4-Carboxylic Acid Hydrochloride
CAS No.	141652-76-8
Molecular Formula	C8H17ClN2O2
Molecular Weight	208.69 g/mol
Synonyms	1-Methyl-4-aminopiperidine-4-carboxylic acid hydrochloride; 4-Amino-1-methyl-4-piperidinecarboxylic acid hydrochloride; 4-Carboxy-1-methyl-4-aminopiperidine hydrochloride; 4-Piperidinecarboxylic acid, 4-amino-1-methyl-, hydrochloride (1:1); (4-Amino-1-methylpiperidin-4-yl)carboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-1-Methylpiperidine-4-Carboxylic Acid HCl is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity (HPLC), and impurity profiles is supplied with each shipment. Our quality protocols are designed to support applications requiring traceability and consistency, including those under cGMP guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.