Description

9(S)-Hepe is a specialized, high-purity eicosapentaenoic acid (EPA) derivative, specifically the 9(S)-hydroperoxy form, with the CAS registry number 141545-44-0. This compound serves as a critical biochemical intermediate and reference standard in advanced lipid research and pharmaceutical development. It is essential for researchers and manufacturers in the pharmaceutical, nutraceutical, and life science industries who require precise bioactive lipid mediators for studying inflammation, resolution pathways, and metabolic processes.

Application

• Biochemical Research: Used as a key intermediate and reference standard in the study of eicosanoid biosynthesis and lipoxygenase pathways.
• Pharmaceutical R&D: Serves as a precursor or analytical standard in the development of novel anti-inflammatory and pro-resolving lipid-based therapeutics.
• Nutraceutical Analysis: Employed as a high-purity standard for the quality control and authentication of advanced ω-3 formulations and metabolites.
• Cell Signaling Studies: Applied in cellular and in vitro models to investigate the role of specific oxylipins in inflammation, immune response, and cellular metabolism.
• Analytical Chemistry: Utilized as a certified reference material (CRM) for calibrating HPLC, LC-MS, and GC-MS systems in lipidomics and metabolomics.
• Enzymology: Acts as a substrate for studying the activity and specificity of lipoxygenase and related enzymes.

Basic Information

Product Name	9(S)-Hepe
CAS No.	141545-44-0
Molecular Formula	C20H30O4
Molecular Weight	334.45 g/mol
Synonyms	(5Z,8Z,11Z,14Z,17Z)-9(S)-Hydroperoxyeicosa-5,8,11,14,17-pentaenoic Acid; 9(S)-HPEPE; 9(S)-HpEPE; 9S-Hydroperoxy-5Z,7E,11Z,14Z,17Z-eicosapentaenoic Acid; 9(S)-HpEPE; 9(S)-HPEPE; 9S-HPEPE; (9S)-HPEPE
EINECS	Contact for details

Quality Control

Every batch of 9(S)-Hepe is produced and analyzed under strict quality management protocols to ensure identity, purity, and stability. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results from multiple orthogonal analytical techniques including HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent degradation via oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizers and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
9(S) Isomer Content	≥ 98% of total HPEPE
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.