Description

2-Iodo-6-(Trifluoromethyl)Pyrazine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is engineered to serve as a critical intermediate in the development of complex molecules, offering unique reactivity from its halogen and electron-deficient pyrazine core. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a precursor for creating functional organic materials, such as ligands for catalysts or components in electronic devices.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings.
• Chemical Library Development: Employed in high-throughput and combinatorial chemistry to generate diverse compound libraries for screening.
• Fluorinated Compound Research: The trifluoromethyl group provides a metabolically stable and lipophilic moiety, making it valuable for medicinal chemistry optimization.

Basic Information

Product Name	2-Iodo-6-(Trifluoromethyl)Pyrazine
CAS No.	141492-94-6
Molecular Formula	C5H2F3IN2
Molecular Weight	273.98 g/mol
Synonyms	6-(Trifluoromethyl)-2-iodopyrazine; 2-Iodo-6-trifluoromethylpyrazine; Pyrazine, 2-iodo-6-(trifluoromethyl)-; Iodo(trifluoromethyl)pyrazine
EINECS	Contact for details

Quality Control

Our 2-Iodo-6-(Trifluoromethyl)Pyrazine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC-MS, and NMR, for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.