Description

(2E)-3-(3-Nitrophenyl)Acryloyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound matters for its role as a key acylating agent, enabling the efficient introduction of the (E)-3-(3-nitrophenyl)acryloyl moiety into target molecules. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of drug candidates, particularly those targeting specific enzyme pathways where the nitrophenyl acrylate structure is a key pharmacophore.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific aromatic acrylate functionalities.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers with tailored optical, electronic, or mechanical properties.
• Ligand and Catalyst Development: Employed in the preparation of complex organic ligands for metal catalysis and asymmetric synthesis.
• Dyestuff and Pigment Manufacturing: Acts as a precursor for synthesizing advanced colorants and photoactive compounds.
• Material Science Research: Utilized in the development of novel organic electronic materials, such as those for OLEDs or organic photovoltaics.
• Bioconjugation Reagent: Facilitates the labeling and modification of biomolecules in biochemical research and diagnostic assay development.

Basic Information

Product Name	(2E)-3-(3-Nitrophenyl)Acryloyl Chloride
CAS No.	141236-48-8
Molecular Formula	C9H6ClNO3
Molecular Weight	211.60 g/mol
Synonyms	(E)-3-(3-Nitrophenyl)acryloyl chloride; trans-3-(3-Nitrophenyl)acryloyl chloride; 3-(3-Nitrophenyl)-2-propenoyl chloride; (2E)-3-(3-Nitrophenyl)prop-2-enoyl chloride; 3-Nitrocinnamoyl chloride; β-(3-Nitrophenyl)acryloyl chloride; (E)-3-(3-Nitrobenzene)acrylic acid chloride
EINECS	Contact for details

Quality Control

Our (2E)-3-(3-Nitrophenyl)Acryloyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and isomeric integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to maximize stability. Due to its hygroscopic and moisture-sensitive nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (E-isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.