Description

Darglitazone is a high-purity pharmaceutical intermediate and research chemical belonging to the thiazolidinedione class. This compound is of significant interest for its role in the development of novel therapeutic agents targeting metabolic disorders. It is primarily utilized by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in drug discovery and synthesis. We supply this material with a focus on consistent quality and reliable global supply chain support.

Application

• Pharmaceutical Research & Development: A key intermediate in the synthesis pathway for thiazolidinedione-based drug candidates.
• Biochemical Studies: Used as a reference standard or active compound in metabolic pathway and receptor binding research.
• Preclinical Development: Serves as a starting material or building block for producing compounds for pharmacological evaluation.
• Academic Research: Employed in university and institutional labs for studies related to diabetes, insulin resistance, and PPAR-gamma modulation.
• Fine Chemical Synthesis: Utilized by custom synthesis and manufacturing organizations (CMOs/CDMOs) for producing specialized, high-value compounds.

Basic Information

Product Name	Darglitazone
CAS No.	141200-24-0
Molecular Formula	C19H20N2O3S
Molecular Weight	356.44 g/mol
Synonyms	Darglitazone; 5-[[4-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione; DRF 2593; DRF-2593; (+-)-Darglitazone; CS-045 analog; Thiazolidinedione derivative; PPAR-gamma agonist precursor
EINECS	Contact for details

Quality Control

Our Darglitazone is manufactured under a quality management system and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Standard quality control includes identity confirmation, purity assay, and control of related substances. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.