Description

n-[(1R,3R,5S)-9-Azabicyclo[3.3.1]Non-3-Yl]-1-Methyl-1H-Indazole-3-Carboxamide Hydrochloride is a high-purity, synthetically derived pharmaceutical intermediate and research chemical of significant interest. This compound is valued for its role as a key building block in the development of novel therapeutic agents, particularly within the field of central nervous system (CNS) research. It is primarily sought by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in advanced medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs) targeting neurological pathways.
• Medicinal Chemistry Research: Used as a core scaffold or building block for designing and synthesizing new chemical entities (NCEs) in drug discovery programs.
• Biochemical Tool Compound: Employed in in vitro and in vivo studies to investigate specific biological targets and mechanisms of action.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing manufacturing processes for clinical trial material.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	n-[(1R,3R,5S)-9-Azabicyclo[3.3.1]Non-3-Yl]-1-Methyl-1H-Indazole-3-Carboxamide Hydrochloride
CAS No.	141136-01-8
Molecular Formula	C17H23ClN4O
Molecular Weight	334.85 g/mol
Synonyms	1-Methyl-N-[(1R,3R,5S)-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide hydrochloride; 1-Methyl-N-(9-azabicyclo[3.3.1]non-3-yl)-1H-indazole-3-carboxamide hydrochloride (stereoisomer); Troparil analogue; β-CIT hydrochloride derivative; Research compound 141136-01-8; Indazole tropane carboxamide hydrochloride; Tropane-based indazole carboxamide HCl salt
EINECS	Contact for details

Quality Control

Our n-[(1R,3R,5S)-9-Azabicyclo[3.3.1]Non-3-Yl]-1-Methyl-1H-Indazole-3-Carboxamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (by chiral HPLC)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.