Description

3-Chloro-5,6-Dimethylpyrazin-2(1H)-One is a high-purity, heterocyclic organic compound with the CAS number 140862-42-6, serving as a versatile and critical building block in advanced chemical synthesis. Its unique pyrazinone core, functionalized with chloro and methyl groups, makes it an essential intermediate for creating complex molecules with targeted biological or material properties. This product is primarily demanded by the pharmaceutical, agrochemical, and specialty chemical industries for research and development, as well as process scale-up.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) agents, antiviral drugs, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Serves as a precursor for the synthesis of organic electronic materials, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Research & Development: Employed as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Acts as a building block for dyes, pigments, and other performance chemicals requiring specific heterocyclic architectures.

Basic Information

Product Name	3-Chloro-5,6-Dimethylpyrazin-2(1H)-One
CAS No.	140862-42-6
Molecular Formula	C6H7ClN2O
Molecular Weight	158.59 g/mol
Synonyms	3-Chloro-5,6-dimethyl-1,2-dihydropyrazin-2-one; 3-Chloro-5,6-dimethyl-2(1H)-pyrazinone; 5,6-Dimethyl-3-chloro-2(1H)-pyrazinone; 2(1H)-Pyrazinone, 3-chloro-5,6-dimethyl-; 3-Chloro-5,6-dimethylpyrazin-2-ol (tautomer); 140862-42-6; 3-Cl-5,6-diMe-pyrazin-2-one
EINECS	Contact for details

Quality Control

Our 3-Chloro-5,6-Dimethylpyrazin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.