Description

1-(2-n-Boc-Aminoethyl)Piperazine is a specialized Boc-protected amine derivative, serving as a crucial building block in advanced organic synthesis. Its primary value lies in providing a protected primary amine functionality, which is essential for the controlled, sequential construction of complex molecules, particularly in peptide and pharmaceutical chemistry. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and biotechnology industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those containing piperazine and ethylenediamine motifs.
• Peptide Mimetic Synthesis: Used in the construction of peptide backbones and side chains where a protected amine is required for selective coupling reactions.
• Linker Chemistry: Employed in the development of chemical linkers for bioconjugation, antibody-drug conjugates (ADCs), and prodrugs.
• Agrochemical Research: Serves as an intermediate in the synthesis of new herbicides, fungicides, and plant growth regulators.
• Material Science: A precursor for functionalized polymers and dendrimers requiring specific amine group placement.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological systems.

Basic Information

Product Name	1-(2-n-Boc-Aminoethyl)Piperazine
CAS No.	140447-78-5
Molecular Formula	C12H25N3O2
Molecular Weight	243.35 g/mol
Synonyms	1-(2-((tert-Butoxycarbonyl)amino)ethyl)piperazine; N-Boc-2-(piperazin-1-yl)ethan-1-amine; tert-Butyl (2-(piperazin-1-yl)ethyl)carbamate; 2-(1-Piperazinyl)ethylamine, N-BOC-; Boc-NH-CH2-CH2-piperazine; N-(tert-Butoxycarbonyl)-2-piperazin-1-ylethylamine; 140447-78-5; 1-(2-(Boc-amino)ethyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-(2-n-Boc-Aminoethyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.