Description

(4-Amino-Piperidin-1-Yl)-(4-Fluoro-Phenyl)-Methanone Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant importance in modern organic synthesis. This compound matters for its role as a key precursor in the development of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system and other therapeutic areas. Pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) need this material for its reliable structural framework in creating novel drug candidates and for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research and development.
• API Synthesis: Used as a key precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Chemical Research: Serves as a versatile scaffold in academic and industrial research for exploring new chemical entities and structure-activity relationships (SAR).
• Process Development: Employed in the optimization and scale-up of synthetic routes from laboratory to pilot plant and commercial production.
• Custom Synthesis: A starting material for the contract manufacturing of specialized fine chemicals and bespoke molecular structures.
• Library Synthesis: Useful for generating focused compound libraries for high-throughput screening in drug discovery programs.

Basic Information

Item	Detail
Product Name	(4-Amino-Piperidin-1-Yl)-(4-Fluoro-Phenyl)-Methanone Hydrochloride
CAS No.	139679-50-8
Molecular Formula	C12H16ClFN2O
Molecular Weight	258.72 g/mol
Synonyms	1-(4-Fluorobenzoyl)-4-aminopiperidine Hydrochloride; 4-Amino-1-(4-fluorobenzoyl)piperidine Hydrochloride; (4-Amino-1-piperidinyl)(4-fluorophenyl)methanone Hydrochloride; 4-Fluoro-N-(4-piperidinyl)benzamide Hydrochloride; 4-Amino-1-piperidinecarboxylic acid (4-fluorophenyl)amide Hydrochloride; 139679-50-8; 4-Amino-1-(4-fluorobenzoyl)piperidine HCl
EINECS	Contact for details

Quality Control

Our (4-Amino-Piperidin-1-Yl)-(4-Fluoro-Phenyl)-Methanone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.