Description

Precorrin 8X is a key intermediate in the complex biosynthetic pathway of vitamin B12 and related corrinoids. This compound matters significantly for researchers and manufacturers developing synthetic routes to cobalamins or studying the intricate enzymatic mechanisms of corrin ring assembly. It is primarily needed by the pharmaceutical, fine chemical, and academic research sectors for advanced biochemical synthesis and metabolic studies.

Application

• Vitamin B12 Biosynthesis Research: Critical intermediate for studying the enzymatic conversion steps in the cobalamin production pathway.
• Pharmaceutical Reference Standard: Used as a high-purity standard in analytical methods for quality control of B12-related products.
• Fine Chemical Synthesis: Serves as a sophisticated building block for the chemical synthesis of corrinoid compounds and analogs.
• Enzymology Studies: Employed in research to understand the function of methyltransferases and other enzymes in the corrin ring closure process.
• Metabolic Pathway Analysis: Utilized in tracing studies to elucidate the later stages of anaerobic and aerobic B12 biosynthesis.

Basic Information

Product Name	Precorrin 8X
CAS No.	139663-56-2
Molecular Formula	C₄₆H₆₆N₄O₁₄
Molecular Weight	899.04 g/mol
Synonyms	Precorrin-8X; 1,19-Seco-cobyrinic acid a,c-diamide, 17,18-didehydro-8,12,18-trimethyl-13-oxo-; (17Z)-17,18-Didehydro-8,12,18-trimethyl-13-oxo-1,19-secocobyrinic acid a,c-diamide; Factor V1a; Anaerobic precorrin 8X
EINECS	Contact for details

Quality Control

Our Precorrin 8X is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.