Description

15-Hydroxy-5,8,11-Eicosatrienoic Acid is a specialized hydroxy fatty acid derivative of arachidonic acid, serving as a key intermediate in the study of eicosanoid biosynthesis and lipid signaling pathways. This compound is valued for its role in biochemical research, particularly in investigating the lipoxygenase and cytochrome P450 metabolic routes. It is essential for researchers and developers in the pharmaceutical, biotechnology, and advanced life science sectors who require high-purity reference standards and synthetic precursors.

Application

• Biochemical Research Standard: Used as a high-purity reference material in lipidomics and eicosanoid research.
• Pharmaceutical Intermediate: Serves as a critical synthetic precursor for developing novel bioactive lipid mediators and drug candidates.
• Enzymology Studies: Employed as a substrate to study the activity and inhibition of lipoxygenase (LOX) and cytochrome P450 enzymes.
• Cell Signaling Research: Utilized in vitro and in vivo to investigate the role of hydroxy-eicosatrienoic acids (HETEs) in inflammation, angiogenesis, and cellular regulation.
• Analytical Chemistry: Acts as a calibration standard for advanced analytical techniques such as LC-MS/MS and HPLC in metabolic profiling.
• Cosmeceutical R&D: Investigated for potential applications in developing advanced skincare formulations targeting inflammatory pathways.

Basic Information

Product Name	15-Hydroxy-5,8,11-Eicosatrienoic Acid
CAS No.	139328-88-4
Molecular Formula	C₂₀H₃₂O₃
Molecular Weight	320.47 g/mol
Synonyms	15-HETE; 15(S)-HETE; 15-Hydroxyeicosatrienoic Acid; 15S-Hydroxy-5Z,8Z,11Z-eicosatrienoic Acid; 15(S)-Hydroxy-5,8,11-cis-eicosatrienoic Acid; 15S-HETE; (15S)-15-Hydroxyicosa-5,8,11-trienoic acid; 15-Hydroxy-5,8,11,14-eicosatetraenoic acid (common misnomer for the trienoic form)
EINECS	Contact for details

Quality Control

Every batch of 15-Hydroxy-5,8,11-Eicosatrienoic Acid is manufactured and analyzed under strict quality management protocols. We guarantee high chemical purity and structural integrity, supported by comprehensive analytical data including NMR, MS, and HPLC. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 97%
Isomeric Purity (Chiral HPLC)	≥ 98% (15S)
Solubility	Soluble in ethanol, DMSO, and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.