Description

(+/-)-α-(2,3-Dimethoxy-Phenyl)-1-[2-(4-Fluorophenyl)Ethyl]-4-Piperidine-Methanol is a high-purity, advanced pharmaceutical intermediate of significant interest in modern organic synthesis. This compound matters for its role as a critical building block in the research and development of novel therapeutic agents, particularly within the central nervous system (CNS) and receptor-targeted drug discovery. Pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers need this material for its structural complexity and potential as a key synthon in creating pharmacologically active molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates targeting neurological and psychiatric disorders.
• Chemical Research & Development: Used in academic and industrial R&D for exploring structure-activity relationships (SAR) and developing new synthetic methodologies.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Medicinal Chemistry: Integral for the construction of complex piperidine-based molecular scaffolds in early-stage drug discovery programs.
• Biochemical Research: Utilized in studies investigating ligand-receptor interactions, particularly those involving fluorophenyl and dimethoxyphenyl pharmacophores.
• Custom Synthesis: A key starting material for the contract manufacturing of specialized, non-commercial compounds for client-specific research projects.

Basic Information

Product Name	(+/-)-α-(2,3-Dimethoxy-Phenyl)-1-[2-(4-Fluorophenyl)Ethyl]-4-Piperidine-Methanol
CAS No.	139290-69-0
Molecular Formula	C22H28FNO3
Molecular Weight	373.47 g/mol
Synonyms	α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol; 1-[2-(4-Fluorophenyl)ethyl]-4-[(2,3-dimethoxyphenyl)(hydroxy)methyl]piperidine; 4-Piperidinemethanol, α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-; 139290-69-0; (±)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol; 1-(4-Fluorophenethyl)-4-[(2,3-dimethoxyphenyl)(hydroxy)methyl]piperidine
EINECS	Contact for details

Quality Control

Our (+/-)-α-(2,3-Dimethoxy-Phenyl)-1-[2-(4-Fluorophenyl)Ethyl]-4-Piperidine-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports research reproducibility and compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.