Description

Pyrazine-2-Carboxamidine Hydrochloride is a high-purity chemical building block and intermediate of significant importance in advanced organic synthesis. Its value lies in its functional group, which serves as a key precursor for constructing heterocyclic compounds, particularly in medicinal chemistry. This product is essential for research and development scientists and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, including kinase inhibitors and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Chemical Biology & Proteomics: Serves as a building block for activity-based probes and other research tools targeting amidine-recognizing enzymes.
• Material Science Research: Employed in the development of organic electronic materials and metal-organic frameworks (MOFs) due to its coordinating nitrogen atoms.
• Academic & Contract Research: A valuable reagent for methodology development and constructing complex molecular libraries in academic and industrial R&D settings.

Basic Information

Product Name	Pyrazine-2-Carboxamidine Hydrochloride
CAS No.	138588-41-7
Molecular Formula	C5H7N4•HCl
Molecular Weight	158.60 g/mol
Synonyms	2-Pyrazinecarboximidamide hydrochloride; Pyrazine-2-carboxamidine HCl; 2-Amidinopyrazine hydrochloride; 2-Carbamimidoylpyrazine hydrochloride; 2-Pyrazinylformamidine hydrochloride; (Pyrazin-2-yl)formamidine hydrochloride; 2-Pyrazinecarboxamidine monohydrochloride
EINECS	Contact for details

Quality Control

Our Pyrazine-2-Carboxamidine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) providing HPLC purity, NMR confirmation, and other critical parameters is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.