Description

3-(Pyrazin-2-Yl)-1,2,4-Thiadiazol-5-Amine CAS NO 138588-23-5 is a high-purity heterocyclic organic compound featuring a fused pyrazine and 1,2,4-thiadiazole core structure. This specialized chemical building block is valued for its unique molecular architecture, which is critical for advanced research and development in medicinal chemistry. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemical intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Serves as a core scaffold for developing new generation herbicides and fungicides with specific modes of action.
• Material Science: Investigated as a monomer or additive for creating specialty polymers and organic electronic materials due to its conjugated system.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition and protein-ligand interactions.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing complex, high-value specialty chemicals.

Basic Information

Product Name	3-(Pyrazin-2-Yl)-1,2,4-Thiadiazol-5-Amine
CAS No.	138588-23-5
Molecular Formula	C6H5N5S
Molecular Weight	179.21 g/mol
Synonyms	5-Amino-3-(pyrazin-2-yl)-1,2,4-thiadiazole; 3-Pyrazin-2-yl-1,2,4-thiadiazol-5-amine; 2-(5-Amino-1,2,4-thiadiazol-3-yl)pyrazine; 1,2,4-Thiadiazol-5-amine, 3-(2-pyrazinyl)-; 138588-23-5; 3-(2-Pyrazinyl)-1,2,4-thiadiazol-5-amine
EINECS	Contact for details

Quality Control

Our production of 3-(Pyrazin-2-Yl)-1,2,4-Thiadiazol-5-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods and purity determination by HPLC. A Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive); therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.