Description

(2R)-2-Phenyl-Piperazine is a chiral piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a crucial chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking high-purity, enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of central nervous system (CNS) active drugs, including potential antidepressants and antipsychotics.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of chiral ligands for asymmetric catalysis, enabling enantioselective transformations.
• Agrochemical Research: Serves as a building block for developing novel chiral pesticides and herbicides with improved efficacy and selectivity.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals requiring specific stereochemistry.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(2R)-2-Phenyl-Piperazine
CAS No.	137766-76-8
Molecular Formula	C10H14N2
Molecular Weight	162.23 g/mol
Synonyms	(R)-2-Phenylpiperazine; (R)-2-Phenyl-piperazine; (2R)-2-Phenylpiperazine; (R)-1,4-Diazacyclohexane, 2-phenyl-; 2-Phenylpiperazine, (R)-; (R)-(-)-2-Phenylpiperazine; UNII-1F2C8U4Z4P; 1,4-Diaza-2-phenylcyclohexane, (R)-
EINECS	Contact for details

Quality Control

Our (2R)-2-Phenyl-Piperazine is produced under strict quality management systems. Each batch is characterized and tested to ensure identity, purity, and enantiomeric excess meet stringent specifications. A comprehensive Certificate of Analysis (COA) detailing results for assay, chiral purity, and related substances is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.