Description

L-693,403 Maleate is a high-purity, non-peptide oxytocin receptor antagonist with significant research and therapeutic potential. This compound is critical for advanced pharmacological studies targeting uterine and reproductive system disorders. It serves as an essential reference standard and active pharmaceutical ingredient (API) intermediate for researchers and developers in the pharmaceutical and biotechnology sectors, particularly those focused on gynecological and obstetric therapeutics.

Application

• Pharmaceutical Research & Development: Primary use as a potent, selective oxytocin receptor antagonist in preclinical and clinical research.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in API manufacturing.
• Active Pharmaceutical Ingredient (API) Intermediate: Key synthetic building block in the production of therapeutic agents for preterm labor and dysmenorrhea.
• Biochemical Assays: Used in high-throughput screening (HTS) and in vitro studies to investigate oxytocin receptor signaling pathways.
• Academic Research: Fundamental tool for universities and research institutions studying neuroendocrinology, social behavior, and stress responses.
• Drug Formulation Studies: Employed in the development of stable and bioavailable dosage forms, leveraging its maleate salt for improved solubility.

Basic Information

Product Name	L-693,403 Maleate
CAS No.	137730-52-0
Molecular Formula	C33H41N5O6 • C4H4O4
Molecular Weight	Contact for details
Synonyms	L-693403 Maleate; L 693,403 Maleate; (2S,4R)-1-[5-Chloro-1-[(2-methylphenyl)methyl]-2-oxo-3H-1,4-benzodiazepin-3-yl]-4-hydroxy-N-[3-(methylamino)propyl]-2-pyrrolidinecarboxamide Maleate; Oxytocin Receptor Antagonist L-693,403; Atosiban Impurity; Benzodiazepine Derivative L693403; 1,4-Benzodiazepine-2-one, 5-chloro-1-[(2-methylphenyl)methyl]-3-[(2S,4R)-4-hydroxy-2-[[[3-(methylamino)propyl]amino]carbonyl]-1-pyrrolidinyl]-2(3H)-, (2Z)-2-butenedioate (1:1)
EINECS	Contact for details

Quality Control

Our L-693,403 Maleate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral chromatography for enantiomeric excess, and spectroscopic identification (IR, NMR, MS). We provide full traceability and Certificates of Analysis (COA) detailing all specifications, ensuring compliance with research and cGMP-grade material standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, 15-25°C (59-77°F), in a dry environment. The product is light-sensitive (store away from light). For long-term storage, consider desiccant and inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.