Description

Piperazine, 2-(2-Fluorophenyl)- (9Ci) CAS NO 137684-18-5 is a fluorinated piperazine derivative, a high-value building block in modern synthetic organic chemistry. Its core value lies in its unique molecular scaffold, which combines a piperazine ring with a fluorinated aromatic system, enabling precise modulation of biological activity and physicochemical properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of central nervous system (CNS) drugs, antipsychotics, and antidepressants.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atom enhances bioavailability and environmental stability.
• Chemical Biology & Medicinal Chemistry: Serves as a privileged scaffold in hit-to-lead optimization and structure-activity relationship (SAR) studies for new therapeutic targets.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with tailored properties.
• Contract Research & Development (CRO/CMO): Supplied to custom synthesis organizations for client-specific molecule development and scale-up projects.

Basic Information

Product Name	Piperazine, 2-(2-Fluorophenyl)- (9Ci)
CAS No.	137684-18-5
Molecular Formula	C10H13FN2
Molecular Weight	180.22 g/mol
Synonyms	2-(2-Fluorophenyl)piperazine; 1-(2-Fluorophenyl)piperazine; 2-Fluorophenylpiperazine; o-Fluorophenylpiperazine; 2-(2-Fluorophenyl)-1,4-diazacyclohexane; 1-(2-Fluorophenyl)piperazine; 2-Fluoro-1-piperazinobenzene
EINECS	Contact for details

Quality Control

Our Piperazine, 2-(2-Fluorophenyl)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.