Description

Darsidomine is a high-purity pharmaceutical intermediate and active ingredient. This compound is critical for the synthesis of advanced therapeutic agents, offering reliable performance and consistent quality for demanding research and manufacturing processes. It is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical producers engaged in the development of novel drug substances.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for clinical research and commercial production.
• Biochemical Research: Used as a reference standard or reagent in pharmacological and metabolic studies.
• Process Development: Serves as a critical starting material for optimizing scalable synthetic routes in process chemistry.
• Contract Manufacturing: Supplied to CMOs for the production of drug candidates under cGMP conditions.
• Academic Research: Employed in university and institutional labs for medicinal chemistry and drug discovery programs.

Basic Information

Product Name	Darsidomine
CAS No.	137500-42-6
Molecular Formula	C14H19N3O3S
Molecular Weight	309.38 g/mol
Synonyms	Darsidomine; 1-(4-Methoxyphenyl)-5-methyl-3-(methylsulfonyl)-1H-pyrazole-4-carboxamide; 4-Carbamoyl-1-(4-methoxyphenyl)-5-methyl-3-methylsulfonylpyrazole; L-754,030; L 754030; L754030
EINECS	Contact for details

Quality Control

Our Darsidomine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical use. Certificates of Analysis (COA) documenting full compliance with specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.