Description

1-Hexadecyl-3-Trifluoroethylglycero-Sn-2-Phosphomethanol is a specialized synthetic phospholipid derivative, a key building block in advanced material science and pharmaceutical research. This compound matters for its unique amphiphilic structure, which enables precise control over membrane properties and surface interactions. It is primarily needed by researchers and manufacturers in the liposome and drug delivery system development, biomimetic membrane studies, and the formulation of specialty surfactants.

Application

• Liposome and Nanoparticle Formulation: As a critical component for constructing stable, functionalized lipid bilayers for targeted drug delivery.
• Biomimetic Membrane Research: Used to create model cell membranes for studying protein-lipid interactions and membrane dynamics.
• Specialty Surfactants & Emulsifiers: Serves as a high-performance surfactant in advanced cosmetic and personal care formulations requiring specific interfacial properties.
• Bioconjugation & Probe Development: Acts as a versatile anchor point for attaching fluorescent dyes, targeting ligands, or other functional groups in diagnostic assays.
• Material Science: Employed in the surface modification of materials to control wettability, biocompatibility, and self-assembly processes.
• Pharmaceutical Intermediates: Used in the synthesis of more complex phospholipid-based active pharmaceutical ingredients (APIs) or excipients.

Basic Information

Item	Details
Product Name	1-Hexadecyl-3-Trifluoroethylglycero-Sn-2-Phosphomethanol
CAS No.	137464-44-9
Molecular Formula	C22H44F3O6P
Molecular Weight	492.55 g/mol
Synonyms	1-Hexadecyl-2-O-methyl-sn-glycero-3-phospho-(N-(2,2,2-trifluoroethyl)carbamate); 1-Palmitoyl-2-O-methyl-sn-glycero-3-phospho(trifluoroethanol); Phosphomethanol, 1-hexadecyl-3-(2,2,2-trifluoroethyl) ether, sn-glycerol derivative; Hexadecyl trifluoroethyl phosphoglyceromethanol; Fluorinated phospholipid analog; sn-2-O-Methyl-1-hexadecyl-3-trifluoroethylphosphoglycerol; (2R)-2-Methoxy-3-(hexadecyloxy)propyl (2,2,2-trifluoroethyl) phosphate
EINECS	Contact for details

Quality Control

Our 1-Hexadecyl-3-Trifluoroethylglycero-Sn-2-Phosphomethanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing specific batch results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.