Description

6-Methoxy-9-[2-O,5-o-Bis(4-Methoxybenzoyl)-β-D-Arabinofuranosyl]-9H-Purine is a sophisticated nucleoside analog derivative, a key building block in advanced pharmaceutical research and development. This compound is critical for the synthesis of novel antiviral and anticancer agents, offering researchers a versatile intermediate with specific functionalization. It is primarily utilized by pharmaceutical R&D departments, biotechnology companies, and academic research institutions focused on nucleoside chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel nucleoside-based antiviral and anticancer therapeutics.
• Antiviral Drug Research: Used in the development of experimental compounds targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a building block for creating potential chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Probe Development: Employed in the design of probes for studying enzyme kinetics and mechanisms involving purine metabolism.
• Nucleoside Chemistry: A valuable substrate for academic and industrial research in modifying sugar and base moieties of nucleosides.
• Process Chemistry & Scale-up: Used in optimizing synthetic routes for the production of more complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	6-Methoxy-9-[2-O,5-o-Bis(4-Methoxybenzoyl)-β-D-Arabinofuranosyl]-9H-Purine
CAS No.	137057-73-9
Molecular Formula	C33H32N4O10
Molecular Weight	644.63 g/mol
Synonyms	9-(2-O,5-O-Bis(4-methoxybenzoyl)-β-D-arabinofuranosyl)-6-methoxy-9H-purine; 6-Methoxy-9-[2,5-di-O-(4-methoxybenzoyl)-β-D-arabinofuranosyl]purine; 6-Methoxy Purine Arabinofuranoside Derivative; 2',5'-Di-O-(4-methoxybenzoyl)-6-methoxy-9-β-D-arabinofuranosylpurine; Protected 6-Methoxy Purine Arabinoside; Ara-6-Methoxypurine Bis(4-methoxybenzoate) Ester
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure structural identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and analytical data is provided with every shipment to support your critical research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.