Description

1-Chloro-1H-Pyrrolo[1,2-A]Pyrazine is a versatile and high-value heterocyclic building block, essential for advanced organic synthesis and pharmaceutical research. Its unique fused ring structure with a chlorine substituent makes it a critical intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key scaffold in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used as a building block for developing new generations of herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Precursor: Acts as a starting material for the synthesis of specialized organic electronic materials and ligands for catalysis.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical reactions involving halogenated heterocycles.
• Custom Synthesis: A foundational component for custom manufacturing and scale-up projects requiring precise, high-purity advanced intermediates.

Basic Information

Product Name	1-Chloro-1H-Pyrrolo[1,2-A]Pyrazine
CAS No.	136927-64-5
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	1-Chloro-1H-pyrrolo[1,2-a]pyrazine; 1-Chloro-1H-pyrrolo[1,2-a]pyrazine; 1H-Pyrrolo[1,2-a]pyrazine, 1-chloro-; 1-Chloropyrrolo[1,2-a]pyrazine; Pyrrolo[1,2-a]pyrazine, 1-chloro-1H-; 1-Chloro-1H-pyrrolo[1,2-a]pyrazine; 136927-64-5 (CAS)
EINECS	Contact for details

Quality Control

Our 1-Chloro-1H-Pyrrolo[1,2-A]Pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.