Description

3,5-Dichloro-2-Iodopyrazine is a halogenated heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring three distinct halogen substituents, makes it a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought after by research chemists and process development scientists for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with specific modes of action.
• Material Science Precursor: Serves as a starting material for creating functionalized pyrazine derivatives used in organic electronics and ligands.
• Cross-Coupling Reactions: The iodine and chlorine atoms provide orthogonal reactivity for sequential Suzuki, Sonogashira, and Buchwald-Hartwig amination reactions.
• Chemical Biology Probes: Utilized in medicinal chemistry to create tagged molecules for target identification and binding studies.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.

Basic Information

Product Name	3,5-Dichloro-2-Iodopyrazine
CAS No.	136866-30-3
Molecular Formula	C4HCl2IN2
Molecular Weight	274.87 g/mol
Synonyms	2-Iodo-3,5-dichloropyrazine; 3,5-Dichloro-2-iodopyrazine; Pyrazine, 3,5-dichloro-2-iodo-; 136866-30-3; 2,6-Dichloro-3-iodopyrazine (alternative numbering); 3-Iodo-5,6-dichloropyrazine
EINECS	Contact for details

Quality Control

Every batch of 3,5-Dichloro-2-Iodopyrazine is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.