Description

1-o-Hexadecyl-2-Desoxy-2-Amino-Sn-Glycerol is a synthetic, high-purity lipid derivative, specifically a long-chain amino-substituted glycerol ether. This compound is a critical building block in advanced lipid chemistry, valued for its role as a functionalized polar head group precursor. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel lipid-based drug delivery systems, including liposomes and lipid nanoparticles (LNPs).

Application

• Pharmaceutical Excipient: A key intermediate in the synthesis of cationic and ionizable lipids for mRNA and siRNA delivery platforms.
• Liposome Formulation: Used to create functionalized liposomal membranes for targeted drug delivery and diagnostic applications.
• Bioconjugation Chemistry: Serves as a linker or spacer molecule for attaching targeting ligands or therapeutic payloads to lipid carriers.
• Biomimetic Membrane Research: Employed in model membrane studies to investigate cell membrane interactions and permeability.
• Cosmetic Actives Carrier: Functions as a component in advanced cosmetic formulations for enhanced skin penetration of active ingredients.
• Biochemical Research: Used as a standard or reagent in lipidomics and metabolic pathway studies.

Basic Information

Product Name	1-o-Hexadecyl-2-Desoxy-2-Amino-Sn-Glycerol
CAS No.	136770-76-8
Molecular Formula	C19H41NO2
Molecular Weight	315.54 g/mol
Synonyms	2-Amino-1-O-hexadecyl-sn-glycerol; 1-O-Hexadecyl-2-amino-2-deoxy-sn-glycerol; 2-Amino-2-deoxy-1-O-hexadecylglycerol; Hexadecyl 2-amino-2-deoxy-sn-glycerol ether; Aminoalkyl glycerol ether; C16-Amino-Glycerol; Lipid amino ether intermediate; sn-1-Hexadecyl-2-amino-2-deoxyglycerol
EINECS	Contact for details

Quality Control

Our 1-o-Hexadecyl-2-Desoxy-2-Amino-Sn-Glycerol is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.