Description

D-Ribo-Hexitol, 3-Deoxy-2-o-Methyl-5,6-o-(1-Methylethylidene)-1-C-Phenyl-4-o-(Phenylmethyl)-, (1R)- CAS NO 136759-84-7 is a high-purity, stereochemically defined carbohydrate derivative, specifically a protected hexitol, designed for advanced synthetic applications. This compound serves as a critical chiral building block and key intermediate in the synthesis of complex bioactive molecules, including nucleoside analogs and pharmaceutical candidates. It is essential for research and development laboratories in the pharmaceutical, agrochemical, and fine chemical sectors that require precise control over molecular architecture.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Glycochemistry Research: Used in the study and development of glycosidase inhibitors, glycomimetics, and complex carbohydrate-based therapeutics.
• Agrochemical Synthesis: Serves as a precursor for creating chiral active ingredients with specific biological activity for crop protection.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Contract Research: A valuable tool for methodological development in organic synthesis and asymmetric catalysis studies.
• Diagnostic Reagent Development: Potential use in creating labeled probes or substrates for enzymatic assays and diagnostic kits.

Basic Information

Item	Detail
Product Name	D-Ribo-Hexitol, 3-Deoxy-2-o-Methyl-5,6-o-(1-Methylethylidene)-1-C-Phenyl-4-o-(Phenylmethyl)-, (1R)-
CAS No.	136759-84-7
Molecular Formula	C23H28O5
Molecular Weight	384.47 g/mol
Synonyms	(1R)-3-Deoxy-2-O-methyl-5,6-O-(1-methylethylidene)-1-C-phenyl-4-O-(phenylmethyl)-D-ribo-hexitol; 1-C-Phenyl-4-O-benzyl-3-deoxy-2-O-methyl-5,6-O-isopropylidene-D-ribo-hexitol; 1-C-Phenyl-4-O-benzyl-3-deoxy-2-O-methyl-5,6-O-(1-methylethylidene)-D-ribo-hexitol; Protected D-ribo-hexitol derivative; Benzyl-protected phenyl-C-hexitol; Isopropylidene-protected hexitol intermediate; Chiral carbohydrate synthon
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality control protocols to ensure consistency and high purity, typically exceeding 97% (HPLC). Our quality assurance includes identity confirmation via spectroscopic methods (NMR, IR) and purity assessment by chromatographic techniques. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment, supporting compliance in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.