Description

14-Debromoaraplysillin I is a specialized marine-derived natural product and a key chemical intermediate in advanced organic synthesis. This compound is valued for its unique structural framework, which serves as a critical scaffold for the research and development of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on creating new therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Research & Development: Serves as a crucial synthetic intermediate or reference standard in the discovery of new drug candidates, particularly in oncology and anti-infective therapeutic areas.
• Medicinal Chemistry: Used as a core building block for structure-activity relationship (SAR) studies and the synthesis of novel analogs with potential biological activity.
• Biochemical Research: Employed as a tool compound in biochemical assays to study specific biological pathways and enzyme interactions.
• Fine Chemical Synthesis: Acts as a high-value precursor in the multi-step synthesis of complex, target-oriented molecules for academic and industrial research.
• Reference Standard: Provides a certified material for analytical method development, validation, and quality control in laboratories.

Basic Information

Product Name	14-Debromoaraplysillin I
CAS No.	136685-29-5
Molecular Formula	C30H39NO4
Molecular Weight	477.64 g/mol
Synonyms	14-Debromo-araplysillin I; Debromoaraplysillin I; Aplysillin derivative; Marine alkaloid intermediate; (3S,5aS,10bS)-3-[(1R)-1-Hydroxyethyl]-2,3,5a,6,7,8,9,10,10b,11-decahydro-5H-pyrrolo[2,1-a]isoquinolin-5-one (related core structure); Pyrroloisoquinoline alkaloid
EINECS	Contact for details

Quality Control

Our 14-Debromoaraplysillin I is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider keeping the material under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.