Description

2,5-Piperazinedione,3-(1-Fluoroethyl)-6-Methyl-,[3R-[3-α-(R*),6-α-]]-(9Ci) is a high-purity, stereochemically defined piperazinedione derivative, a key structural motif in medicinal chemistry. This compound is valued for its role as a sophisticated chiral building block and intermediate in the synthesis of complex pharmaceutical agents. It is primarily targeted at research and development organizations, process chemists, and manufacturers in the pharmaceutical and fine chemical industries seeking to develop novel active pharmaceutical ingredients (APIs) and advanced therapeutic candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of potential drug candidates, particularly those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Peptidomimetic Development: Acts as a constrained scaffold for designing and synthesizing peptidomimetics and protease inhibitors.
• Asymmetric Synthesis: Employed as a starting material or intermediate in asymmetric catalytic processes to introduce stereogenic centers.
• Reference Standard: Utilized as an analytical standard for quality control and method development in API manufacturing.
• Fine Chemical Synthesis: Incorporated into the production of specialty chemicals and advanced materials requiring specific stereochemistry.

Basic Information

Item	Details
Product Name	2,5-Piperazinedione,3-(1-Fluoroethyl)-6-Methyl-,[3R-[3-α-(R*),6-α-]]-(9Ci)
CAS No.	136606-95-6
Molecular Formula	C7H11FN2O2
Molecular Weight	174.17 g/mol
Synonyms	3-[(1R)-1-Fluoroethyl]-6-methylpiperazine-2,5-dione; (3R,6R)-3-[(1R)-1-Fluoroethyl]-6-methylpiperazine-2,5-dione; (3R,6R)-3-[(R)-1-Fluoroethyl]-6-methyl-2,5-piperazinedione; 3-(1-Fluoroethyl)-6-methyl-2,5-piperazinedione (stereoisomer); Fluorinated Diketopiperazine Derivative; Chiral Fluorinated DKP; F-DKP Intermediate
EINECS	Contact for details

Quality Control

Every batch of our 2,5-Piperazinedione derivative is produced and tested under a strict quality management system. We ensure high chiral purity and chemical integrity through advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.