Description

2-Chloro-5-Ethoxypyrazine is a versatile pyrazine derivative, a key heterocyclic building block prized for its unique chemical reactivity. This compound matters for its role as a crucial intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and advanced material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the pyrazine core's bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials.
• Flavor & Fragrance Chemistry: Acts as a building block for creating complex aroma compounds, given the significance of alkoxypyrazines in sensory profiles.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for use in bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	2-Chloro-5-Ethoxypyrazine
CAS No.	136309-11-0
Molecular Formula	C6H7ClN2O
Molecular Weight	158.59 g/mol
Synonyms	5-Ethoxy-2-chloropyrazine; 2-Chloro-5-ethoxypyrazine; 2-Chloro-5-ethoxy-1,4-diazine; 136309-11-0; 5-Ethoxy-2-chloro-1,4-diazine; Chloroethoxy pyrazine; 2-Chloro-5-ethoxy-pyrazine
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Ethoxypyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.