Description

(S)-Etodolac Monosodium Salt CAS NO 136172-37-7 is the single enantiomer, sodium salt form of the non-steroidal anti-inflammatory drug (NSAID) Etodolac. This high-purity chiral intermediate is critical for pharmaceutical R&D and manufacturing, offering superior specificity and reduced side-effect profiles compared to racemic mixtures. It is primarily utilized by pharmaceutical companies and advanced research institutions engaged in developing novel analgesic and anti-inflammatory therapeutics.

Application

• Active Pharmaceutical Ingredient (API) Intermediate: Key chiral building block for the synthesis of enantiomerically pure (S)-Etodolac.
• Pharmaceutical Research & Development: Used in preclinical and clinical studies to investigate the efficacy and pharmacokinetics of the specific enantiomer.
• Analytical Reference Standard: Serves as a high-purity standard for HPLC, LC-MS, and other analytical methods in quality control laboratories.
• Process Chemistry & Scale-Up: Employed in optimizing and scaling manufacturing processes for chiral NSAID production.
• Formulation Development: Used in developing final dosage forms, such as tablets or capsules, containing the pure enantiomer.

Basic Information

Product Name	(S)-Etodolac Monosodium Salt
CAS No.	136172-37-7
Molecular Formula	C17H20NNaO3
Molecular Weight	309.34 g/mol
Synonyms	(S)-Etodolac Sodium Salt; (+)-(S)-Etodolac Sodium Salt; Sodium (S)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetate; (S)-Etodolac Na Salt; Dexetodolac Sodium Salt; (S)-Etodolac Sodium; Etodolac Impurity D (Sodium Salt); LODINE(S) Sodium Salt
EINECS	Contact for details

Quality Control

Our (S)-Etodolac Monosodium Salt is manufactured under strict quality systems. Each batch is subjected to comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets stringent specifications for pharmaceutical use. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Chiral Purity (Enantiomeric Excess)	≥99.0%
Water Content (KF)	≤2.0%
Related Substances (HPLC)	Total impurities ≤1.5% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.