Description

4-Bromobicyclo[2.2.2]octan-1-amine is a specialized bicyclic organic compound featuring a bromine substituent and a primary amine functional group. This unique structure makes it a valuable versatile building block in advanced organic synthesis and pharmaceutical research. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its rigid bicyclic scaffold.
• Ligand and Catalyst Development: The amine group allows for chelation to metals, making it useful for creating novel ligands in asymmetric catalysis.
• Material Science Monomer: Acts as a building block for synthesizing specialty polymers with unique thermal or mechanical properties.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular probe.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and exploring new chemical spaces.

Basic Information

Product Name	4-Bromobicyclo[2.2.2]octan-1-amine
CAS No.	135908-39-3
Molecular Formula	C8H14BrN
Molecular Weight	204.11 g/mol
Synonyms	1-Amino-4-bromobicyclo[2.2.2]octane; 4-Bromoadamantan-1-amine (common misnomer based on structure); Bicyclo[2.2.2]octan-1-amine, 4-bromo-; 4-Bromo-1-aminobicyclo[2.2.2]octane; 4-Bromobicyclo[2.2.2]octyl-1-amine
EINECS	Contact for details

Quality Control

Our 4-Bromobicyclo[2.2.2]octan-1-amine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.