Description

Endo-3-Amine-9-Methyl-9-Azabicyclo[3,3,1]Nonane Dihydrochloride is a high-purity, bicyclic amine hydrochloride salt of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of complex pharmaceutical molecules, particularly those targeting neurological pathways. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for drug discovery and process optimization.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for neurological and psychiatric drug candidates.
• Asymmetric Synthesis: Utilized as a chiral amine auxiliary or resolving agent in stereoselective chemical reactions.
• Medicinal Chemistry Research: Serves as a core scaffold for constructing novel compound libraries in drug discovery programs.
• Agrochemical Development: Intermediate in the synthesis of advanced crop protection agents and pesticides.
• Catalyst Ligand Synthesis: Building block for creating novel ligands used in homogeneous catalysis.
• Fine Chemical Production: Used in the custom synthesis of specialty chemicals for various high-value industrial applications.

Basic Information

Product Name	Endo-3-Amine-9-Methyl-9-Azabicyclo[3,3,1]Nonane Dihydrochloride
CAS No.	135906-03-5
Molecular Formula	C9H18N2·2HCl
Molecular Weight	239.18 g/mol
Synonyms	9-Methyl-9-azabicyclo[3.3.1]nonan-3-amine dihydrochloride (endo-); 3-Amino-9-methyl-9-azabicyclo[3.3.1]nonane dihydrochloride; Tropane-3-amine, N-methyl-, dihydrochloride, endo-; endo-3-Amino-9-methyl-9-azabicyclo[3.3.1]nonane dihydrochloride; 9-Methyl-3-aminonortropane dihydrochloride; endo-N-Methylnortropinone amine dihydrochloride
EINECS	Contact for details

Quality Control

Our Endo-3-Amine-9-Methyl-9-Azabicyclo[3,3,1]Nonane Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure compliance with stringent specifications for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (endo-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.