Description

Pyrazino[1,2-A]Benzimidazole, 1,2,3,4-Tetrahydro-1-Methyl-, (S)- (9Ci) is a high-purity, chiral organic compound of significant interest in advanced pharmaceutical research and development. This specific stereoisomer is valued for its role as a key synthetic intermediate or a potential pharmacophore in the creation of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex heterocyclic molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or infectious diseases.
• Medicinal Chemistry Research: Used as a core scaffold or a derivatization starting point in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Asymmetric Synthesis: The defined (S)- stereochemistry makes it a valuable chiral synthon for constructing enantiomerically pure compounds in process chemistry.
• Reference Standard: Employed as an analytical standard in method development and quality control for related pharmaceutical processes.
• Biochemical Research: May be utilized in vitro studies to investigate interactions with specific enzymes or biological receptors.

Basic Information

Item	Detail
Product Name	Pyrazino[1,2-A]Benzimidazole, 1,2,3,4-Tetrahydro-1-Methyl-, (S)- (9Ci)
CAS No.	135875-08-0
Molecular Formula	C12H13N3
Molecular Weight	199.25 g/mol
Synonyms	(S)-1,2,3,4-Tetrahydro-1-methylpyrazino[1,2-a]benzimidazole; (S)-1-Methyl-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazole; 1,2,3,4-Tetrahydro-1-methylpyrazino[1,2-a]benzimidazole, (S)-; Pyrazino[1,2-a]benzimidazole, 1,2,3,4-tetrahydro-1-methyl-, (S)-; (S)-TBZP derivative; Chiral tetrahydro-pyrazinobenzimidazole
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and enantiomeric purity. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.