Description

(S)-5-Oxopiperazine-2-Carboxylic Acid is a high-purity, non-proteinogenic amino acid derivative featuring a chiral center and a piperazinone backbone. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Peptidomimetic Scaffold: Used to design and synthesize constrained peptide analogs and protease inhibitors due to its rigid piperazinone structure.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in stereoselective chemical reactions to introduce chirality.
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies and as a standard in analytical method development.
• Ligand Synthesis: Useful for creating complex ligands for catalysis or metal-organic frameworks (MOFs).
• Academic & Industrial R&D: Serves as a versatile building block for exploratory chemistry in medicinal and process chemistry laboratories.

Basic Information

Product Name	(S)-5-Oxopiperazine-2-Carboxylic Acid
CAS No.	135630-97-6
Molecular Formula	C5H8N2O3
Molecular Weight	144.13 g/mol
Synonyms	(S)-5-Oxopiperazine-2-carboxylic acid; (2S)-5-Oxo-1,4-diazinane-2-carboxylic acid; (S)-Piperazine-2-carboxylic acid, 5-oxo-; L-5-Oxopiperazine-2-carboxylic acid; (S)-PCA-5-one; 2-Piperazinecarboxylic acid, 5-oxo-, (2S)-; (S)-2-Carboxy-5-oxopiperazine; (S)-5-Oxo-2-piperazinecarboxylic acid
EINECS	Contact for details

Quality Control

Our (S)-5-Oxopiperazine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥98%), chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.