Description

3-Hydroxy-5,8,11,14-Eicosatetraenoic Acid is a specialized hydroxy fatty acid derivative of arachidonic acid, playing a significant role as a bioactive lipid mediator in various biochemical pathways. This compound is valued for its utility as a key reference standard and research chemical in the study of eicosanoid metabolism and inflammation. It is primarily sought by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on lipidomics, drug discovery, and metabolic disease research.

Application

• Biochemical Research: Used as a critical reference standard in lipidomics and metabolomics studies for the identification and quantification of eicosanoid pathways.
• Pharmaceutical Development: Serves as a key intermediate or analytical standard in the research and development of anti-inflammatory and metabolic disorder therapeutics.
• Enzyme Activity Studies: Employed as a substrate or product in assays investigating the activity of lipoxygenase and cytochrome P450 enzymes.
• Cell Signaling Research: Utilized to study the role of hydroxy-eicosatetraenoic acids (HETEs) in cellular signaling, inflammation, and immune response mechanisms.
• Academic Laboratories: A fundamental tool for graduate and post-doctoral research in biochemistry, pharmacology, and cell biology.
• Diagnostic Kit Manufacturing: Can be incorporated as a calibrator in specialized diagnostic kits for measuring lipid mediators in biological samples.

Basic Information

Product Name	3-Hydroxy-5,8,11,14-Eicosatetraenoic Acid
CAS No.	135295-02-2
Molecular Formula	C₂₀H₃₂O₃
Molecular Weight	320.47 g/mol
Synonyms	3-HETE; 3-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic Acid; 3-Hydroxyarachidonic Acid; 3(S)-HETE; 3(S)-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic Acid; 3-Hydroxy-5,8,11,14-all-cis-eicosatetraenoic Acid; 3-Hydroxy-5-cis,8-cis,11-cis,14-cis-eicosatetraenoic Acid; 3-Hydroxyeicosatetraenoic Acid
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure the identity, purity, and stability of our research chemicals. Each batch of 3-Hydroxy-5,8,11,14-Eicosatetraenoic Acid is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR to confirm specification compliance. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and chromatographic data is provided with every shipment to support your research integrity and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 97%
Solubility	Soluble in ethanol, DMSO, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.