Description

Didemnaketal A is a complex, biologically active marine natural product belonging to the didemnaketal class of compounds. This compound is of significant interest for its potent and selective inhibitory activity against HIV-1 protease, making it a valuable research tool in antiviral and medicinal chemistry studies. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on virology and novel drug discovery.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and a lead compound in the discovery of novel HIV-1 protease inhibitors.
• Antiviral Mechanism Studies: Used in biochemical and cell-based assays to investigate the structure-activity relationship (SAR) and inhibition mechanisms of HIV-1 protease.
• Medicinal Chemistry Synthesis: Acts as a complex molecular scaffold for the semi-synthesis or total synthesis of new analogs with potential therapeutic applications.
• Academic Research: Employed in university and institutional labs for studies in organic synthesis, natural product chemistry, and bioactivity screening.
• Biotechnology Applications: Used in high-throughput screening (HTS) platforms to identify and validate new targets for antiviral drug development.

Basic Information

Product Name	Didemnaketal A
CAS No.	135257-49-7
Molecular Formula	C27H38O7
Molecular Weight	474.59 g/mol
Synonyms	Didemnaketal A; NSC 643051; L-696,474; (1R,2S,5S,8S,11S,12S,15S,18S)-5,12,18-Tris(1,1-dimethylethyl)-8-[(1S)-1-hydroxy-1-methylethyl]-15-(2-methylpropyl)-4,17-dioxa-14-azatricyclo[13.3.1.12,6]icosa-2(19),3,5,16-tetraene-3,10,13,16-tetrone
EINECS	Contact for details

Quality Control

Our Didemnaketal A is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation. Keep the material in its original container away from incompatible substances.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.