Description

Thielocin A1Alpha is a specialized, high-purity chemical compound identified by CAS No. 134892-23-2. This product is valued for its role as a potent and selective inhibitor of the enzyme β-1,3-glucan synthase, making it a critical tool in biochemical and pharmacological research. It is primarily sought after by research institutions and pharmaceutical developers working on antifungal drug discovery and the study of fungal cell wall biosynthesis.

Application

• Biochemical Research: Used as a reference standard and investigative tool in enzymatic studies targeting β-1,3-glucan synthase.
• Antifungal Drug Discovery: Serves as a key pharmacophore and lead compound in the development of novel antifungal agents.
• Microbiology Studies: Employed to study fungal physiology, cell wall integrity, and mechanisms of action for various antifungal compounds.
• Pharmaceutical R&D: Utilized in high-throughput screening assays and target validation within infectious disease research programs.
• Academic Research: Applied in university and institutional labs for fundamental research into glycosyltransferase enzymes and their inhibitors.

Basic Information

Product Name	Thielocin A1Alpha
CAS No.	134892-23-2
Molecular Formula	C38H62O14
Molecular Weight	742.9 g/mol
Synonyms	Thielocin A1 alpha; Thielocin A1-α; Benzenepropanoic acid, β-[[(2S,3S,4S,5S,6R)-4-[(2S,3S,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydro-2H-pyranyl]oxy-2-tetrahydro-2H-pyranyl]oxy-3,5,6-trihydroxy-2-tetrahydro-2H-pyranyl]oxy]-α-hydroxy-, (αR)-; β-1,3-Glucan synthase inhibitor; Fungal enzyme inhibitor
EINECS	Contact for details

Quality Control

Every batch of Thielocin A1Alpha is produced and tested under stringent quality management protocols to ensure identity, purity, and consistency. We provide comprehensive analytical data, including HPLC purity profiles and spectroscopic confirmation (NMR, MS). A Certificate of Analysis (COA) detailing all test results is supplied with each shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.